When you smoke or vape, nicotine reaches the brain within 1020 seconds and binds to nicotinic acetylcholine receptors (nAChRs)
References: [1] Alicia M Allen, Andrea H Weinberger, Reagan R Wetherill, Carol L Howe, Sherry A McKee, Oral Contraceptives and Cigarette Smoking: A Review of the Literature and Future Directions, Nicotine & Tobacco Research, Volume 21, Issue 5, May 2019, Pages 592601, [2] Kaufmann A, Hitsman B, Goelz PM, Veluz-Wilkins A, Blazekovic S, Powers L, Leone FT, Gariti P, Tyndale RF, Schnoll RA
The second, is that when Im working down in the shop on the bandsaw or table saw or drafting board or whatever and concentrating on what Im doing and turn my head to the right, a straight pipe never touches my shoulder - a curved pipe, on the other hand, will touch my shoulder and because Im so involved in my work, I wont notice it until the burning sensation of the hot pipe registers in my brain
This evolution is influenced by lifestyle psychology and cultural shifts, where authenticity and self-awareness are just as important as outward presentation
